I voted for this beatbox cover of "Trouble" to win Response of the Year ...

http://www.youtube.com/v/XyKJfRpu8_E?list=PLbpi6ZahtOH733qzMtJyBRCnkwKs-0XeV&version=3&autohide=1&attribution_tag=levmOIz7P976kM0SDy3ASA&autoplay=1&showinfo=1&feature=share

Yes, this too!!